Lagido, C., Zhang, C., Atira, L. Vieyra-Ramirez, A., Kakouli-Duarte, T., Stürzenbaum S.R. (2025). Chapter 14: Caenorhabditis elegans and Ecotoxicogenomics in Nematodes as Environmental Indicators: From Theory to Practice (CABI). 222-249.
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Zhang, C., Cabreiro, F., Barron, L.P., Stürzenbaum, S.R. (2025). Carpamazepine-exposed earthworms are characterized by tissue-specific accumulation patterns and transcriptional profiles. Environ Int 198:109357.
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Zhang, C., Barron, L.P., Stürzenbaum, S.R. (2025). Pollution of soil by pharmaceuticals: implications for metazoan and environmental health. Annu Rev Pharmacol Tox 65:12.1-12.9.
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Chen, Y., Jiang, Y., Sarvanantharajah, N., Apirakkan, O., Yang, M., Milcova, A., Topinka J., Abbata, V., Arlt, V.M., Stürzenbaum, S.R. (2024). Genome-modified Caenorhabditis elegans expressing the human cytochrome P450 (CYP1A1 and CYP1A2) pathway: and experimental model for environmental carcinogenesis and pharmacological research. Environ Int 194:109187.
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Andric, A., Niederwanger, M., Albertini, E., Jansen-Dürr, P., Stürzenbaum, S.R., Dallinger, R., Pedrini-Martha, V., Weiss, A.K.H. (2024). A multi-domain snail metallothionein increases resistance and fitness in Caenorhabditis elegans. Sci Rep14(1):25589.
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Almutairi, N., Khan, N., Harrison-Smith, A., Arlt, V.M., Stürzenbaum, S.R. (2024). Stage-specific exposure of Caenorhabditis elegans to cadmium identifies unique transcriptomic response cascades and an uncharacterised cadmium responsive transcript. Metallomics 2:16(5):mfae016.
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Karpov, M.A., Hobbs, C., Jayasinghe, S.N., Stürzenbaum, S.R. (2024). Metallomic mapping of gut and brain in heavy metal exposed earthworms: A novel paradigm in ecotoxicology. Biochem Biophys Res Commun 709: 149827.
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Weishaupt, A-K., Lamann, K., Tallarek, E., Pezacki, A.T., Matier, C.D., Schwerdtle, T., Aschner, M., Chang, C.J., Stürzenbaum, S.R., Bornhorst J. (2024). Dysfunction in atox-1 and ceruloplasmin alters labile Cu levels and consequently Cu homeostasis in C. elegans. Front Mol Biosci 11:1354627.
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Essig, Y.J., Leszczyszyn, O.I., Almutairi, N., Harrison-Smith, A, Blease, A., Zeitoun-Ghandour, S., Webb, S.M., Blindauer, C.A., Stürzenbaum S.R. (2024). Juggling cadmium detoxification and zinc homeostasis: a division of labour between the two C.elegans metallothioneins. Chemosphere 350:141021.
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Chen, Y., Arlt, V.M., Stürzenbaum S.R. (2023). MosSCi mediated exogenous gene expression is modulated by genomic positioning. Biotechnol J 18(9):e2300062.
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Richardson, A.K., Irlam, R.C., Wright, H.R., Mills, G.A., Fones, G.R., Stürzenbaum S.R., Cowan, D.A., Neep, D.J., Barron, L.R. (2022). A miniaturized passive sampling-based workflow for monitoring chemicals of emerging concern in water. Sci Total Environ 839: 156260.
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Gómez, L., Niegowska, M., Navarro, A., Amendola, L., Arukwe, A., Ait-Aissa, S., Balzamo, S., Barreca, S., Belkin, S., Bittner, M., Blaha, L., Buchinger, S., Busetto, M., Carere, M., Colzani, L., Dellavedova, P., Denslow, N., Escher, B.I., Hogstrand, C., Khan, E.A., König, M., Kroll, K.J., Lacchetti, I., Maillot-Marechal, E., Moscovici, L., Potalivo, M., Sanseverino, I., Santos, R., Schifferli, A., Schlichting, R., Sforzini, S., Simon, E., Shpigel, E., Sturzenbaum, S., Vermeirssen, E., Viarengo, A., Werner, I., Lettieri, T. (2021). Estrogenicity of chemical mixtures revealed by a panel of bioassays. Sci Total Environ 785:147284.
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Zhang, C., Barron, L., Stürzenbaum S. (2021). The transportation, transformation and (bio)accumulation of pharmaceuticals in the terrestrial ecosystem. Sci. Total Environ. 781: 146684.
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Baesler, J., Michaelis, V., Stiboller, M., Haase, H., Aschner, M., Schwerdtle, T., Sturzenbaum, S.R., Bornhorst, J. (2021).Nutritive Manganese and Zinc overdosing in aging C. elegans result in a metallothionein-mediated alteration in metal homeostasis. Mol Nutr Food Res 65(8): e2001176.
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Richardson, A.K., Chadha, M., Wright, H.R., Mills, G.A., Fones, G.R., Gravell A., Stürzenbaum S., Cowan, D.A. Neep, J., Barron, L.P (2021). Rapid direct analyisis of river water and machine learning-assisted suspect screening of emerging contaminants in passive sampler extracts. Anal Methods 13(5): 595-606
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Abbass, M., Chen, Y., Arlt, V.M., Stürzenbaum S.R. (2021). Benzo[a]pyrene and Caenorhabditis elegans: defining the genotoxic potential in an organism lacking the classical CYP1A1 pathway. Arch Toxicol 95(3): 1055-1069.
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Alsaleh, S.A. Barron L., Stürzenbaum S. (2021). Perchlorate detection via an invertebrate biosensor. Anal Methods 13(3): 327-336.
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Katsiamides, A., and Stürzenbaum S. (2021). Cryptic speciation and blurred species boundaries of the earthworm: A challenge for soil-based toxicological risk assessments. Comp Biochem Physiol C: Toxicol. Pharmacol. 239: 108880.
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De la Parra-Guerra, A, Stürzenbaum S, Olivero-Verbel, J. (2020). Intergenerational Toxicity of Nonylphenol Ethoxylate (NP-9) in Caenorhabditis elegans. Ecotoxicol Env Saf 197:110588.
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Hirvonen, L.M., Nedbal, J., Almutairi, N., Phillips, T.A. Becker, W., Conneely, T., Milnes, J., Cox, S., Stürzenbaum, S.R., Suhling, K. (2020). Lighsheet fluorescence lifetime imaging microscopy with wide-field time-correlated single photon counting. J Biophotonics 13(2): e201960099.
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Prendergast-Miller, M.T. , Katsiamides, A., Abbass, M., Stürzenbaum, S.R., Thorpe, K.L., Hodson, M.E. (2019). Polyester-derived microfibre impacts on soil-dwelling earthworm Lumbricus terrestris. Env Pollut 251: 453-459.
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Nie,Y., Stürzenbaum, S.R. (2019). Proanthocyanidins of natural origin: molecular mechanisms and implications for lipid disorder and aging associated diseases. Adv Nutr 10(3):464-478.
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Chaudhuri, P., Iman, H.T., Essig, Y., Krasauskas, J., Webb, S.M. Blindauer, C.A., Stürzenbaum, S.R. (2018). Molecular genetic and biochemical characterization of a putative family of zinc metalloproteins in Caenorhabditis. elegans. Metallomics 10(12):1814-1823.
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Nie,Y., Littleton, B., Kavanagh, T., Abbate,V., Bansal, S., Richards, D., Hylands, P., Stürzenbaum, S.R. (2017). Proanthocyanidin trimer gallate modulates lipid deposition and fatty acid desaturation in C. elegans. FASEB J. 31(11):4891-4902..
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M'kandawire, E., Mierek-Adamska, A., Stürzenbaum, S.R., Choongo, K., Yabe, J., Mwase, M. Saasa, N., Blindauer, C.A. (2017). Metallothionein from wild populations of the African catfish Clarias gariepinus: from sequence, protein expression and metal binding properties to transcriptional biomarker of metal pollution (2017). Int. J. Mol. Sci 18(7), 1548.
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Gonzales-Moragas, L., Yu, S-M., Benseny-Cases, N., Stürzenbaum, S.R., Roig, A., Laromaine, A. (2017). Toxicogenomics of iron oxide nanoparticles in the nematode C.elegans. Nanotoxicology 11(5):647-657.
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Nie, Y, Stürzenbaum, S.R. (2017). Chapter 11: Model Nematodes in obesity research. In Animal Models for the Study of Human Disease, Second Edition (Ed P. Michael Conn) Elsevier.
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Gonzales-Moragas, L., Berto, P., Vilches, C., Quidant, R., Kolovou, A., Santarella-MEllwig, R., Schwab, Y., Stürzenbaum, S.R., Roig, A., Laromaine, A. (2017). In vivo testing of gold nanoparticles using the Caenorhabditis elegans model organism. Acta Biomater. 53:598-609.
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Imanikia, S., Galea, F., Nagy, E., Phillips, D.H., Stürzenbaum, S.R., Arlt, V.M. (2016). The application of the comet assay to assess the genotoxicity of environmental pollutants in the nematode Caenorhabditis elegans. Environ Toxicol Pharmacol. 45:356-361.
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Homa, J., Stürzenbaum, S.R., Kolaczkowska, E. (2016). Metallothionein 2 and Heat Shock Protein 72 protect Allolobophora chlorotica from cadmium but not nickel or copper exposure: body malformation and coelomocyte functioning. Arch. Environ. Contam. Toxicol. 71(2):267-277.
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Essig,Y.J., Webb, S.M., Stürzenbaum, S.R. (2016). Deletion of phytochelatin synthase modulates the metal accumulation pattern of cadmium exposed C. elegans. Int. J. Mol. Sci. 17: 257.
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Kowald, G.R., Stürzenbaum, S.R., Blindauer, C.A. (2016). Earthworm Lumbricus rubellus MT-2: Metal binding and protein folding of a true Cadmium-MT. Int. J. Mol. Sci. 17: 65.
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Imanikia, S., Hylands, P., Stürzenbaum, S.R. (2015). The double mutation of cytochrome P450's and fatty acid desaturases affect lipid regulation and longevity in C. elegans . Biochem. Biophys. Rep. 2:172-8.
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Saul, N., Stürzenbaum, S.R., Chakrabarti, S., Baberschke, N., Lieke, T., Putschew, A., Kochan, C., Menzel, R., Steinberg, C.E.W. (2015). Adsorbable organic bromine compounds (AOBr) in aquatic samples: a nematode based toxicogenomic assessment of the exposure hazard. Environ. Sci. Pollut. R. 22(19):14862-73.
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Hoeckner, M., Dallinger R., Stürzenbaum, S.R. (2015). Metallothionein gene activation in the earthworm (Lumbricus rubellus). Biochem. Biophys. Res. Commun. 460(3):537-42.
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Qabazard, B., Stürzenbaum, S.R. (2015). Hydrogen Sulfide: A New Approach to Lifespan Enhancement and Healthy Ageing? Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide in the Handbook of Experimental Pharmacology 20:269-87.
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Saul, N., Chakrabarti, S., Stürzenbaum, S.R., Menzel, R., Steinberg, C.E.W. (2014). Neurotoxic action of microcystin-LR is reflected in the transcriptional stress response of Caenorhabditis elegans. Chemico-Biological Interactions 223C: 51-7.
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Carvalho, R.N., Arukwe, A., Ait-Aissa, S., Bado-Nilles, A., Balzamo, S., Baun, A., Belkin, S., Blaha, L., Brion, F., Conti, D., Creusot, N.,Essig, Y., Ferrero, V.E.V., Flander-Putrle, V., Furhacker, M., Grillari-Voglauer, R., Hogstrand, C., JonaÅ¡, A., Loos, R., Lundebye, A-K., Modig, C., Olsson, P-E., Pillai, S., Polak, N., Potalivo, M., Sanchez, W., Schifferli, A., Schirmer, K., Sforzini, S., Stürzenbaum,S.R., Softeland, L., Turk, V., Viarengo, A., Werner, I., Yagur-Kroll, S., Zounkova, R., Lettieri T. (2014) Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they? Toxicol. Sci. 141(1):218-33.
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Saul, N., Baberschke, N., Chakrabarti, S., Stürzenbaum,S.R., Lieke, T., Menzel, R., Jonas, A., Steinberg , C.E.W. (2014). Two organobromines trigger lifespan, growth, reproductive, and transcriptional changes in Caenorhabditis elegans.Environ. Sci. Pollut. Res. 21(17): 10419-31.
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Aitlhadj, L., Stürzenbaum,S.R. (2014). C. elegans in regenerative medicine: a simple model for a complex discipline. Drug Discov. Today 19(6): 730-4.
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Polak, N., Read, D.S., Jurkschat, K., Matzke, M., Kelly, F.J., Spurgeon, D.J., Stürzenbaum, S.R. (2014). Metalloproteins and phytochelatin synthase may confer protection against zinc oxide nanoparticle induced toxicity in Caenorhabditis elegans. Comp. Biochem. Physiol. C Toxicol. Pharmacol.. 160:75-85.
ViewAbstract
Qabazard, B., Li, L., Gruber, J., Peh, M.T., Ng, L.F., Kumar, S.D., Rose, P., Tan, C.-H., Dymock B.W., Wei., F., Swain, S.C., Halliwell, B., Stürzenbaum, S.R. Moore, P.K. (2014). Hydrogen sulfide is an endogenous regulator of ageing in C.elegans. Antioxid. Redox Signaling 20(16):2621-30.
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Qabazard, B., Ahmed, S., Li, L., Arlt,. V.M., Moore, P.K., Stürzenbaum, S.R. (2013). C.elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cycl-2.
PloS One 8(11) e80135.
View Abstract
Ristow, O., Hohlweg-Majert, B., Stürzenbaum, S.R., Kehl, V., Koerdt, S., Hahnefeld, L., Pautke, C., 2013). Therapeutic elastic tape reduces morbidity after wisdom teeth removal-a clinical trial. Clin. Oral. Investig. 18(4): 1205-1212.
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Saul, N., Pietsch, K., Stürzenbaum, S.R.,Menzel, R., Steinberg, C.E.W. (2013). Hormesis with tannins: free of charge or cost-intensive? Chemosphere 93(6): 1005-8.
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Aitlhadj, L., Stürzenbaum, S.R. (2013). The toxicological assessment of two anti-obesity drugs in C. elegans. Toxicol. Res. 2:145-50.
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Stürzenbaum, S.R., Hoeckner, M., Panneerselvam, A., Levitt, J., Bouillard, J.-S., Taniguchi, S., Dailey, L.-A., Ahmad Khanbeigi, R.A., Thanou, M., Rosca, E.V., Suhling, K., Zayats, A., Green, M. (2013). Biosynthesis of luminescent quantum dots in an earthworm. Nature Nanotechnol. 8(1):57-60.
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Highlighted in:
Tilley, R.D., Cheong S. (2013). Nanomaterials: Earthworms lit with quantum dots. Nature Nanotechnology
- Methods in Brief (2013). An earthworm QD factory. Nature Methods
- Earthworms roped into making quantum dots (Jan 2013).New Scientist
- Worms turn metal into semiconductors (Jan 2013). NBC NEWS
- The quantum earthworm (Dec 2012). National Geographic
- Highjacking worm guts to produce tiny semiconductors (Dec 2012) Discover Magazine
Steinberg, C.E.W., Pietsch, K., Saul, N., Menzel, S., Swain, S.C., Stürzenbaum,S.R., Menzel, R. (2013). Transcript expression patterns illuminate the mechanistic background of hormesis in Caenorhabditis elegans Maupas. Dose Response 11:558-76.
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Kille, P., Andre, J., Anderson, C., Ang, H.N., Bruford, M.W., Bundy,J.G., Donnelly, R., Hodson, M.E., Juma, E., Morgan, A.J., Stürzenbaum, S.R., Spurgeon, D.J. (2013). DNA Sequence variation and methylation in an arsenic tolerant earthworm population. Soil Biol Biochem. 57:524-32.
View Abstract
Imanikia, S., Stürzenbaum, S.R. (2013). Chapter 12: Invertebrates in Obesity Research, a worm’s perspective. In: Animal Models for the Study of Human Disease (Ed P. Michael Conn) Elsevier . pp 265-75.
View Abstract
Stürzenbaum, S.R., Aschner, M., Freedman, J.H. (2012). Toxicogenomics in non-mammalian species-Editorial. Front Genet. 3:216.
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Pautke, C., Kreutzer, K., Weitz, J., Knödler, M., Münzel, D., Wexel, G., Otto, S., Hapfelmeier, A., Stürzenbaum, S.R., Tischer, T. (2012). Bisphosphonate related osteonecrosis of the jaw: A minipig large animal model. Bone 51(3):592-9.
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Pietsch, K., Saul, N., Swain, S.C., Menzel, R., Steinberg, C.E.W., Stürzenbaum, S.R. (2012). Meta-analysis of global transcriptomics reveals suggests conserved genetic pathways to be of responsible for Quercetin and Tannic acid mediated longevity in C. elegans. Front. Genet. 3:48.
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Menzel, R., Menzel, S., Swain, S.C., Pietsch, K., Tiedt, S., Witczak, J., Stürzenbaum, S.R., Steinberg, C.E.W. (2012). The nematode Caenorhabditis elegans, stress and aging: Identifying the complex interplay of genetic pathways following the treatment with humic substances. Front. Genet. 3:50.
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Baylay, A.J., Spurgeon, D.J., Svendsen, C., Griffin, J.L., Swain, S.C., Stürzenbaum, S.R., Jones, O.A. (2012). A metabolomics based test of independent action and concentration addition using the earthworm Lumbricus rubellus. Ecotoxicology 21(5):1436-47.
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Jones, O.A.H., Swain, S.C., Svendsen, C., Griffin, J.L., Stürzenbaum, S.R., Spurgeon, D.J. (2012). A potential new method of mixture effects testing using metabolomics and Caenorhabditis elegans. J. Prot. Res. 11(2): 1446-53.
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Mast, G., Otto, S.,Mücke, M., Schreyer, C., Bissinger, O., Kolk, A., Wolff, K.D., Ehrenfeld, M., Stürzenbaum, S.R., Pautke, C. (2012). Incidence of maxillary sinusitis and oro-antral fistulae in bisphosphonate-related osteonecrosis of the jaw. J. Cranio. Max. Surg. 40(7):568-71.
View Abstract
Otto, S., Schreyer, C., Hafner, S., Mast, G., Ehrenfeld, M., Stürzenbaum, S.R., Pautke, C. (2012).Bisphosphonate-related osteonecrosis of the jaws - characteristics, risk factors, clinical features, localization and impact on oncological treatment. J. Cranio. Max. Surg. 40(4):303-9.
View Abstract
Höckner, M., Dallinger, R., Stürzenbaum, S.R. (2011). Nematode and snail metallothioneins. J. Biol. Inorg. Chem. 16(7): 1057-1065.
View AbstractSaul, N., Pietsch, K., Stürzenbaum,S.R, Menzel, R. Steinberg C.E.W. (2011). The diversity of polyphenol action in C.elegans. J. Nat. Prod. 74(8):1713-1720.
View AbstractZeitoun-Ghandour, S.,Leszczyszyn, O.I., Blindauer, C.A., Geier, F.M., Bundy, J.G., Stürzenbaum, S.R. (2011). C.elegans metallothioneins: response to and defence against ROS toxicity. Mol. BioSyst. 7(8):2397-406.
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Pietsch, K., Saul, N.,Chakrabarti, Stürzenbaum, S.R., Menzel, R. Steinberg C.E.W. (2011). Hormetins, Antioxidants and Prooxidants: Defining Quercetin-, Caffeic acid- and Rosmarinic acid- mediated life extension in C.elegans. Biogerontology 12(4):329-47.
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Otto, S., Schreyer, C., Hafner,S., Mast, G., Ehrenfeld, M., Stürzenbaum, S.R., Pautke, C. (2011). Bisphosphonate-related osteonecrosis of the jaws - characteristics, risk factors, clinical features, localization and impact on oncological treatment. J. Cranio. Max. Surg. (in press).
View Abstract
Pautke, C., Otto, S., Kirchner,T., Kolk, A., Ehrenfeld, M., Stürzenbaum, S.R., Wolff, K-D. (2011). Bisphosphonate related osteonecrosis of the jaw - manifestation in a microvascular liliac bone transplant. Oral Oncology 47(5):425-9.
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Otto, S., Abu-Id, M.H., Fedele, S., Warnke, P.H., Becker, S.T., Kolk, A., Mücke, T., Mast, G., Köhnke, R., Volkmer, E., Haasters, F., Lieger, O., Iizuka, T., Porter, S., Campisi, G., Colella, G., Ploder, O., Nef, A., Wiltfang, J., Ehrenfeld, M., Kreusch, T., Wolff, K-D., Stürzenbaum, S.R., Schieker, M., Pautke, C. (2011). Osteoporosis and Bisphosphonates - Related Osteonecrosis of the Jaw: not just a sporadic coincidence. J. Cranio. Max. Surg. 39(4):272-277.
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Wren, J.F., Kille, P.,Spurgeon, D.J., Swain, S.C., Stürzenbaum, S.R., Jager, T. (2011). Application of physiologically based modelling and transcriptomics to probe the systems toxicology of aldicarb for Caenorhabditis elegans (Maupas 1900). Ecotoxicology 20(2): 397-408.
View Abstract
Pautke, C., Bauer, F., Otto, S., Tischer, T., Steiner, T., Weitz, J., Kreutzer, K., Hohlweg-Majert, B., Wolff, K.D., Hafner, S., Mast, G., Ehrenfeld, M., Stürzenbaum, S.R., Kolk, A. (2011). Fluorescence-Guided Bone Resection in Bisphosphonate-Related Osteonecrosis of the Jaws: First Clinical Results of a Prospective Pilot Study. J Oral Maxillofac Surg. 69(1): 84-91.
View Abstract
Leszczyszyn, O.I., Zeitoun-Ghandour, S., Stürzenbaum, S.R., Blindauer, C.A. (2011). Tools for metal ion sorting: In vitro evidence for partitioning of zinc and cadmium in C.elegans metallothionein isoforms. Chem. Comm. 47(1): 448-450.<
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Aitlhadj, L., Silva de Ávila, D., Benedetto, A., Aschner, M., Stürzenbaum, S.R. (2011). Environmental exposure, obesity and Parkinson’s disease: lessons from fat and old worms. Environ. Health Persp. 119(1):20-28.
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Andre,J., Stürzenbaum,S.R., Kille, P., Morgan, A.J. and Hodson, M.E. (2010). Metal bioaccumulation and cellular fractionation in an epigeic earthworm (Lumbricus rubellus): the interactive influences of population exposure histories, site-specific geochemistry and mitochondrial genotype. Soil Biol. Biochem. 42(9): 1566-1573.
highlighted in Planet Earth online
Zeitoun-Ghandour, S., Charnock, J.M., Hodson, J.M., Leszczyszyn, O.I., Blindauer, C.A., Stürzenbaum, S.R. (2010). The two C.elegans metallothioneins (CeMT1 and CeMT2) discriminate between essential zinc and toxic cadmium. FEBS J. 277: 2531–2542.
View Abstract
Saul, N., Pietsch, K., Menzel, R. Stürzenbaum, S.R., Steinberg, C.E.W. (2010). The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets Hormesis. J. Gerontol. Biol. Sci. 65(6):626-35.
View Abstract »» highlighted in Frankfurter Allgemeine (FAZ)
Worm Gene Data Flags Environmental Toxicity (2010). Computer Power User Magazine 10(4): 105.
Aitlhadj, L., Stürzenbaum, S.R. (2010). The use of FUdR can cause prolonged longevity in mutant nematodes. Mech. Age. Develop. 131(5):364-5.
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Spurgeon, D.J., Jones, O.A.H., Dorne, J-L. C.M., Svendsen, C., Swain, S.C., Stürzenbaum, S.R. (2010). Systems toxicology approaches for understanding the joint effects of environmental chemical mixtures – model and non-model species. Sci. Total Environ. 408(18):3725-34.
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Swain, S.C.*, Wren, J.F.*, Stürzenbaum, S.R.*, Kille, P., Morgan, A.J., Jager, T., Jonker, M.J., Hankard, P.K., Svendsen, C., Owen, J., Hedley, B.A., Blaxter, M.L. and Spurgeon, DJ. (2010). Linking toxicant molecular and physiological mode of action in Caenorhabditis elegans. BMC Systems Biology 4:32. 
* contributed equally. View Abstract
Otto, S., Hafner, S., Mast, G., Tischer, T., Abu-Id, M.-H., Volkmer, E., Schieker, M., Stürzenbaum, S.R., Wolff, K.-D., Ehrenfeld, M., Pautke, C., (2010). Bisphosphonate-related osteonecrosis of the jaw – the missing part in the puzzle of pathogenesis? J. Oral. Maxillofac. Surg. 68(5):1158-61.
View Abstract
Hurley, A.J., Stürzenbaum, S.R. and Kille, P. (2010). Chapter 7: Transcriptomic analysis of metallotoxicity: mapping the molecular cascades underlying cadmium toxicosis during embryonic development in the rainbow trout (Oncorhynchus mykiss), in Essential and non-essential metal metabolism in aquatic organisms (Eds. N. Bury, I. Sokolova and R. Handy). Taylor and Francis, pp.183-199.
Mongkoldhumrongkul, N., Swain, S.C., Jayasinghe, S.N., Stürzenbaum, S.R. (2010). Bio-electrospraying the nematode Caenorhabditis elegans: studying whole genome transcriptional responses and key life cycle parameters. J. R. Soc. Interface 7:595-601.
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Solinger, J., Paolinelli, R., Klöß, H., Scorza, F.B., Marchesi, S., Sauder, U., Mitsushima, D., Capuani, F., Stürzenbaum, S.R., Cassata, G. (2010). The C.elegans Elongator Complex Regulates Neuronal a-Tubulin Acetylation. PLoS Genetics 6(1): e1000820. doi:10.1371/journal.pgen.1000820.
View Abstract
Roelofs, D., Morgan, A.J., Stürzenbaum, S.R. (2010). The significance of genome-wide transcriptional regulation in the evolution of stress tolerance. Evol. Ecol. 24: 527-539.
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Pautke, C., Bauer, F., Bissinger, O., Tischler, T., Kreutzer, K., Steiner, T., Weitz, J., Otto, S., Wolff, K-D., Stürzenbaum, S.R., Kolk, A. (2010). Tetracycline bone fluorescence: a valuable marker for the osteonecrosis characterization and therapy. J. Oral. Maxillofac. Surg. 68(1): 125-129.
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Andre, J., King, R. A., Stürzenbaum, S.R., Kille, P., Hodson, M. E. and Morgan, A. J. (2010). Molecular genetic differentiation in earthworms inhabiting a heterogeneous Pb-polluted landscape. Environ. Pollut. 158(3): 883-890.
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Software models aid gene expression toxin study. BBC News Technology section.
Jiang, G C-T. Hughes, S., Stürzenbaum, S.R., Evje, L., Syversen, T., Aschner, M. (2009) Caenorhabditis elegans metallothioneins protect against toxicity induced by depleted uranium. Toxicol. Sci. 111(2):345-354.
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Andre, J., Charnock, J., Stürzenbaum, S.R., Kille, P., Morgan, A.J., Hodson, M.E. (2009). Metal speciation in field populations of earthworms with multi-generational exposure to metalliferous soils: cell fractionation and high energy synchrotron analyses. Environ. Sci. Technol. 43(17): 6822–6829.
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Hughes, S., Bundy, J., Want, E., Kille, P., Stürzenbaum, S.R. (2009). The metabolomic responses of Caenorhabditis elegans to cadmium are largely independent of metallothionein status, but dominated by changes in cystathionine and phytochelatins. J. Prot. Res. 8(7):3512-3519.
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Saul, N., Pietsch, K., Menzel, R., Stürzenbaum, S.R., Steinberg, C.E.W. (2009). Catechin induced longevity in C.elegans: from key regulator genes to disposable soma. Mech. Age. Develop. 130(8):477-86.
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Menzel, R., Swain, S.C., Hoess, S., Claus, E., Menzel, S., Steinberg, C.E.W., Reifferscheid, G., Stürzenbaum, S.R. (2009). Gene expression profiling to characterize sediment toxicity - a pilot study using Caenorhabditis elegans whole genome microarrays. BMC Genomics 10:160.
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Pietsch, K., Saul, N., Menzel, R., Stürzenbaum, S.R., Steinberg, C.E.W. (2009). Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43. Biogerontology (5):565-78.
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Menzel, R., Steinberg, C.E.W., Stürzenbaum, S.R. (2009). Gene expression in response to environmental pollution using genomic DNA microarry analysis. Chapter 11: Nematodes as Biological Indicators. (Eds M. Wilson and T. Kakouli-Duarte) CABI Publishing, Wallingford, UK, 253-274.
Guo, Q., Sidhu, J.K., Ebbels, T.M.D., Rana, F., Spurgeon, D.J, Svendsen, C., Stürzenbaum, S.R., Kille, P., Morgan, A.J., Bundy, J.G. (2009). Validation of metabolomics for toxic mechanism of action screening with the earthworm Lumbricus rubellus. Metabolomics 5(1) 72-83.
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Stürzenbaum, S.R., Andre J., Kille, P. and Morgan A.J. (2009). Earthworm genomes, genes and proteins: the (re)discovery of Darwin's worms. Proc. R. Soc. B 276(1658): 789-797.
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highlighted in NatureNews
Pautke, C., Bauer, F., Tischer, T., Kreutzer, K., Weitz, J., Kesting, M., Kolk, A., Stürzenbaum, S.R., Wolff, K.-D. (2009). Fluorescence guided bone resection in bisphosphonate associated osteonecrosis of the jaws. J. Oral. Maxillofac. Surg. 67(3): 471-476.
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Stürzenbaum, S.R. (2009). Chapter 7: Earthworm and nematode metallothioneins, in Metal Ions in Life Sciences, Volume 5: Metallothioneins and Related Chelators (Eds. A. Sigel, H. Sigel and R.K.O. Sigel) Royal Society of Chemistry Publishing, Cambridge, UK. Met. Ions Life Sci. 5, 183–197.
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Calafato, S., Swain, S.C., Hughes, S., Kille, P. and Stürzenbaum, S.R.(2008). Knockdown of Caenorhabditis elegans cutc-1 exacerbates the sensitivity towards high levels of copper. Toxicol. Sci. 106(2), 384–391.
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Steinberg, C.E., Stürzenbaum, S.R., Menzel, R. (2008). Genes and Environment - striking the fine balance between sophisticated biomonitoring and true functional environmental genomics. Sci. Total Environ. 400: 142-161.
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Owen, J., Hedley, A., Svendsen, C., Wren, J.F., Jonker,M., Hankard, K.P., Lister, L., Stürzenbaum, S.R., Morgan, A.J., Spurgeon, D.J., Blaxter, M., Kille, P. (2008). Transcriptome profiling of developmental and xenobiotic responses in a keystone soil animal, the oligochaete annelid Lumbricus rubellus. BMC Genomics 9: 226.
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highlighted in Times Online and NERC
Bundy, J.G., Sidhu, J.K., Rana, F., Spurgeon, D.J., Svendsen, C., Wren, J.F., Stürzenbaum, S.R., Morgan, A.J. and Kille, P. (2008). "Systems toxicology" approach indentifies coordinated metabolomic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus. BMC Biology 6: 25.
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Highlighted in Times Online and NERC
Svendsen, C., Owen, J., Kille, P., Wren, J.F., Jonker, M., Hedley, A., Morgan, A.J., Blaxter, M., Stürzenbaum, S.R., Hankard, P., Lister, L., Spurgeon, D.J. (2008). Comparative transcriptomic responses to chronic cadmium, fluoranthene and atrazine exposure in Lumbricus rubellus. Environ. Sci. Technol. 42, 4208-4214.
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Suzuki, K., Suzuki, T. , Honda, M., Stürzenbaum, S.R. and Gamou, S. (2008). Construction of a Bacterial Artificial Chromosome (BAC) library and the genomic analysis of valosine-containing proteins in the earthworm Eisenia fetida. Eur. J. Soil Biology, 44, 202-206.
Homa, J., Stürzenbaum, S.R., Morgan, A.J. and Plytycz, B. (2007). Disrupted homeostasis in coelomocytes of Eisenia fetida and Allobophora chloratica exposed dermally to heavy metals. Eur. J. Soil Biology 43, S273-280.
Menzel, R., Yeo, H.L., Rienau, S., Li, S., Steinberg, C.E. and Stürzenbaum, S.R. (2007). Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans. J. Mol. Biol. 370(1):1-13.
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Morgan, A.J., Kille, P. and Stürzenbaum, S.R. (2007). Microevolution and Ecotoxicology of Metals in Invertebrates. Environ. Sci. Technol. 41, 1085-1096.
Hughes, S. and Stürzenbaum, S.R. (2007). Single and double metallothionein knockout in the nematode C.elegans reveals cadmium dependent and independent toxic effects on life history traits. Environ. Pollut. 145: 395-400.
Neher, D.A. and Stürzenbaum, S.R. (2006). Extra long PCR, an identifier of DNA adducts in single nematodes (Caenorhabditis elegans). Comp. Biochem. Physiol.C (Toxicol Pharmacol.) 144: 279-285.
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Ngu, T.T., Stürzenbaum, S.R. and Stillman, M.J. (2006). Cadmium binding studies to the earthworm Lumbricus rubellus metallothionein by electrospray mass spectrometry and circular dichroism spectroscopy. Biochem. Biophys. Res. Comm. 351: 229–233.
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Olchawa E., Bzowska, M., Stürzenbaum, S.R., Morgan, A.J. and Plytycz, B. (2006). Dermal exposure to metal ions affects the coelomocyte-bacteria balance in earthworms. Environ. Pollut. 142(2): 373-381.
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Cholewa, J., Feeney, G.P, O’Reilly, M., Stürzenbaum, S.R., Morgan, A.J. and Plytycz, B. (2006). Species specific autofluorescence in earthworm coelomocytes. Folia Histochemica et Cytobiologica 44(1):65-71.
Suzuki, T., Honda, M., Matsumoto, S., Stürzenbaum, S.R., and Gamou, S. (2005). Valosine-containing proteins (VCP) in an annelid: Identification of a novel spermatogenesis related factor. Gene 362: 11-18.
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Menzel, R., Stürzenbaum, S.R., Bärenwaldt, A., Kulas, J. and Steinberg, C.E.W. (2005). Humic material induces behavioral and global transcriptional responses in the nematode Caenorhabditis elegans. Environ. Sci. Technol. 39 (21): 8324 - 8332.
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Spanier, B.*, Stürzenbaum, S.R.*, Holden-Dye, L.M. and Baumeister, R. (2005). C.elegans neprilysin NEP-1: an effector of locomotion and pharyngeal pumping. J. Mol. Biol. 352: 429 - 437 (*contributed equally).
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Stürzenbaum, S.R., Arts, M.S.J. and Kammenga, J.E. (2005). Molecular cloning and characterisation of Cpn60 in the free-living nematode Plectus acuminatus. Cell Stress Chaperon.10 (2): 79–85.
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Langdon,C.J., Winters, C., Stürzenbaum, S.R., Morgan, A.J., Charnock, J.M., Meharg, A.A., Piearce, T.G., Lee, P.H. and Semple, K.T. (2005). Ligand Arsenic complexation and immunoperoxidase detection of metallothionein in the earthworm Lumbricus rubellus inhabiting Arsenic-rich soil. Environ. Sci. Technol. 39 (7): 2042 - 2048.
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Galay Burgos, M., Winters, C., Stürzenbaum, S.R., Randerson, P.F., Kille, P. and Morgan, A.J. (2005). Cu and Cd effects on the earthworm Lumbricus rubellus in the laboratory: multivariate statistical analysis of relationships between exposure, biomarkers, and ecologically-relevant parameters. Environ. Sci. Technol. 39 (6): 1757 -1763.
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Homa, J., Olchawa E., Stürzenbaum, S.R., Morgan, A.J. and Plytycz, B. (2005). Early-phase immunodetection of metallothionein and heat shock proteins in extruded earthworm coelomocytes after dermal exposure to metal ions. Environ. Pollut. 135: 275-280.
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Stürzenbaum, S.R., Georgiev, O., Morgan, A.J. and Kille, P. (2004). Cadmium detoxification in earthworms: from genes to cells. Environ. Sci. Technol. 38 (23): 6283 - 6289.
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Swain, S.C., Keusekotten, K., Baumeister, R., Stürzenbaum, S.R. (2004). C.elegans metallothioneins: new insights into the phenotypic effects of cadmium toxicosis. J. Mol Biol. 341: 951-959.
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Spurgeon, D.J., Stürzenbaum, S.R., Svendsen, C., Hankard, P.K., Morgan, A.J., Weeks J.M. and Kille P. (2004). Toxicological, cellular and gene expression responses in earthworms exposed to copper and cadmium. Comp. Biochem. Physiol.C (Toxicol Pharmacol.)138:11-21.
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Morgan, A.J., Stürzenbaum, S.R., Winters, C., Grime, G.W., AbdAziz, N.A and Kille P. (2004). Differential metallothionein expression in earthworm (Lumbricus rubellus) tissues. Ecotox. Environ. Safety 57: 11-19.
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Stürzenbaum, S.R., Parkinson, J., Blaxter, Morgan, A.J., Kille, P. and Georgiev, O. (2003). The earthworm EST sequencing project. Pedobiologia, 5: 447-451.
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Galay, M., Spurgeon, D.J., Weeks, J.M., Stürzenbaum, S.R., Morgan, A.J. and Kille, P. (2003). Developing a new method for soil pollution monitoring using molecular genetic biomarkers. Biomarkers, 8: 229-239.
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Stürzenbaum, S.R. (2003). Worms have turned for Julie, South Wales Echo, 4th December, page 34. View Article
Stürzenbaum, S.R., Winters, C., Galay, M., Morgan, A.J. and Kille, P. (2001). Metal ion trafficking in earthworms - identification of a cadmium specific metallothionein. J. Biol. Chem., 276: 34013-34018.
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Stürzenbaum, S.R. and Kille, P. (2001). Control genes in quantitative molecular biological techniques: the variability of invariance. Comp. Biochem. Physiol. B., 130: 281-289.
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Stürzenbaum, S.R., Cater, S. Morgan, A.J. and Kille, P. (2001). Earthworm preprocarboxypeptidase: a copper responsive enzyme. BioMetals,14: 85-94.
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Gruber, C., Stürzenbaum, S.R., Gehrig, P., Sack, R., Hunziker, P., Berger, B. and Dallinger, R. (2000). (Cd)-Metallothionein from Eisenia foetida: Isolation and characterization of self-sufficient one-domain protein. Eur. J. Biochem., 267: 573-582.
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Dallinger, R., Berger, B., Gruber, C., Hunziker, P. and Stürzenbaum, S.R. (2000). Metallothionein in terrestrial invertebrates: structural aspects, biological significance, and implications for their use as biomarkers. Cell. Mol. Biol., 46: 331-346.
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Stürzenbaum, S.R. (1999). Transfer RNA reduces the formation of primer artifacts during quantitative PCR. BioTechniques, 27: 50-52.
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Stürzenbaum, S.R., Morgan, A. J. and Kille, P. (1999). Characterization and quantification of earthworm cyclophilins: identification of invariant and heavy metal responsive isoforms. Biochim. Biophys. Acta, 1489: 467-473.
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Morgan, A.J., Stürzenbaum, S.R., Winters, C. and Kille, P. (1999). Cellular and molecular aspects of metal sequestration and toxicity in earthworms. Invertebrate Reproduction and Development, 36: 17-24.
Kille, P., Stürzenbaum, S.R., Galay, M., Winters, C. and Morgan, A.J. (1999). Molecular diagnosis of pollution impact in earthworms - towards integrated biomonitoring. Pedobiol., 43: 602-607.
Morgan, A.J., Stürzenbaum, S.R. and Kille, P. (1999). A short overview of molecular biomarker strategies with particular regard to recent developments on earthworms. Pedobiol., 43: 574-584.
Morgan, A.J., Winters, C. and Stürzenbaum, S.R. (1999). Chapter 15: Electron Microscopy: X-Ray Microanalysis Techniques. Methods in Molecular Medicine Biology, (Ed. Hajibagheri) Humana Press, Totowa, USA, 245-276.
Morris, C.A., Stürzenbaum, S.R., Nicolaus, B., Morgan, A.J., Harwood, J.L. and Kille, P. (1999). Identification and characterisation of metallothioneins from environmental indicator species as potential biomonitors. Metallothionein IV, (Ed. Klaassen) Birkhaeuser Verlag, Basel, Switzerland, 621-627.
Stürzenbaum, S.R., Kille, P. and Morgan, A.J. (1998). The identification, cloning and characterization of earthworm metallothionein. FEBS Lett. 431: 437-442.
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Stürzenbaum, S.R., Kille, P. and Morgan, A.J. (1998). Identification of heavy metal induced changes in the expression patterns of the translationally controlled tumor protein (TCTP) in the earthworm L. rubellus. Biochim. Biophys. Acta, 1398: 294-304.
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Stürzenbaum, S.R., Kille, P. and Morgan, A.J. (1998). Heavy metal induced molecular responses in the earthworm: genetic fingerprinting by directed differential display. Appl. Soil Ecol., 9: 495-500.
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Mariño, F., Stürzenbaum, S.R. and Morgan, A.J. (1998). An ecotypic influence on metal accumulation by earthworms revealed by strontium exposure. Appl. Soil Ecol., 9: 471-474.
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Mariño, F., Stürzenbaum, S.R., Morgan, A.J., and Kille, P. (1998). Cu-Cd interactions in earthworms maintained in laboratory microcosms: the examination of a copper paradox. Comp. Biochem. Physiol. C., 120: 217-223. View.
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Stürzenbaum, S.R., Kille, P. and Morgan, A.J. (1998). Chapter 17: The identification of new biomarkers as a response to heavy metal pollution. Earthworm Ecotoxicology, (Ed. Sheppard et al.) SETAC Press, 215-224.
